SCHEMBL10654110

SCHEMBL10654110

[SiH3]CN(C1CCCC1)C1CCCC1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 6/20 0.33
ADH1C P00326 4/20 0.33
ADH4 P08319 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23319719 0.97 ADH1A (0.35) ADH1AADH1CADH4SLC6A2SLC6A4
SCHEMBL10652717 0.97 ADH1A (0.35) ADH1AADH1CADH4SLC6A2SLC6A4
SCHEMBL516222 0.75 ADH1A (0.46) ADH1AADH1CADH4SLC6A2SLC6A4
SCHEMBL5703310 0.73 ADH1A (0.50) ADH1AADH1CALDH1A1CYP1A2CYP2D6
SCHEMBL28872600 0.73 ADH1A (0.50) ADH1AADH1CALDH1A1CYP1A2CYP2D6
SCHEMBL5703370 0.73 ADH1A (0.50) ADH1AADH1CALDH1A1CYP1A2CYP2D6
SCHEMBL23038 0.73 ADH1A (0.50) ADH1AADH1CALDH1A1CYP1A2CYP2D6
SCHEMBL3109021 0.71 ADH1A (0.38) ADH1AADH1CADH4SLC6A2SLC6A4
SCHEMBL2066596 0.71 ADH1A (0.42) ADH1AADH1CALDH1A1CYP1A2CYP2D6
SCHEMBL10170019 0.71 ADH1A (0.39) ADH1AADH1CADH4SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0112434-B1 HYDROGEN BEARING SILYL CARBAMATES UNION CARBIDE CORPORATION (US) 1988-08-17 EP disclosed
EP-0273456-A2 Vapor phase alcoholysis of aminosilanes and carbamatosilanes UNION CARBIDE CORPORATION (US) 1988-07-06 EP disclosed
US-4730074-A Vapor phase alcoholysis of aminosilanes and carbamatosilanes UNION CARBIDE CORPORATION (US) 1988-03-08 US disclosed
EP-0098912-B1 PROCESS FOR THE PREPARATION OF ALKOXYHYDRIDOSILANES UNION CARBIDE CORPORATION (US) 1986-04-23 EP disclosed
EP-0098911-A1 Improved process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
EP-0098912-A1 Process for the preparation of alkoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
US-4395564-A REACTING AN ALCOHOL WITH SILYL-AMINE UNION CARBIDE CORPORATION (US) 1983-07-26 US disclosed
US-4384131-A Process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1983-05-17 US disclosed