Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.64 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.64 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.64 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.64 |
| ▸ | RARB | P10826 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24370665 | 0.93 | GRIN2D (0.71) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL26298725 | 0.88 | GRIN2D (0.65) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL13548350 | 0.87 | RARB (0.61) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL10601735 | 0.87 | GRIN2D (0.52) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL10485816 | 0.87 | GRIN2D (0.52) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL10356210 | 0.87 | GRIN2D (0.63) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL10356642 | 0.87 | GRIN2D (0.63) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL10356640 | 0.87 | GRIN2D (0.63) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL10356173 | 0.87 | GRIN2D (0.63) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL10485692 | 0.85 | GRIN2D (0.54) | GRIN2DGRIN2AGRIN2BGRIN2CRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257048-A1 | OPTICALLY ACTIVE COMPOUNDS. | MERCK PATENT GMBH (DE) | 1988-03-02 | — | — | EP | disclosed |
| WO-1987005018-A2 | OPTICALLY ACTIVE COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-08-27 | — | — | WO | disclosed |