Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 4/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10485816 | 0.98 | GRIN2D (0.52) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL10601735 | 0.98 | GRIN2D (0.52) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL10486263 | 0.85 | GRIN2D (0.42) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL10654243 | 0.85 | GRIN2D (0.64) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL28261661 | 0.84 | RARB (0.56) | RARBFOLH1ALDH1A1 | |
| SCHEMBL10485710 | 0.83 | ANPEP (0.46) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL8841547 | 0.83 | RARB (0.62) | RARBALDH1A1ADRB3ADRB1NFKB1 | |
| SCHEMBL10486236 | 0.82 | TBXAS1 (0.44) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL10485939 | 0.82 | FFAR1 (0.49) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 | |
| SCHEMBL10485933 | 0.82 | BLM (0.47) | GRIN2DGRIN2AGRIN2BGRIN2CRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194693-B1 | POLYPRENYL COMPOUNDS, PROCESSES FOR PREPARING THEM, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Eisai Co., Ltd. (JP) | 1989-07-26 | — | — | EP | claimed |
| US-4788330-A | Polyprenyl compounds | EISAI CO., LTD. (JP) | 1988-11-29 | — | — | US | claimed |
| EP-0194693-A1 | Polyprenyl compounds, processes for preparing them, and pharmaceutical composition containing them | Eisai Co., Ltd. (JP) | 1986-09-17 | — | — | EP | claimed |
| US-4883916-A | ANTICHOLESTEROL, ANTIARTERIOSCELEROSIS | EISAI CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| EP-0194693-B1 | POLYPRENYL COMPOUNDS, PROCESSES FOR PREPARING THEM, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Eisai Co., Ltd. (JP) | 1989-07-26 | — | — | EP | disclosed |
| EP-0110397-B1 | POLYPRENYL COMPOUND AND DRUG CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 1989-06-14 | — | — | EP | disclosed |
| US-4788330-A | Polyprenyl compounds | EISAI CO., LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| US-4762829-A | ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1988-08-09 | — | — | US | disclosed |
| US-4742058-A | AMIDES, ANTICOAGULANTS | EISAI CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0194693-A1 | Polyprenyl compounds, processes for preparing them, and pharmaceutical composition containing them | Eisai Co., Ltd. (JP) | 1986-09-17 | — | — | EP | disclosed |
| EP-0110397-A2 | Polyprenyl compound and drug containing the same | Eisai Co., Ltd. (JP) | 1984-06-13 | — | — | EP | disclosed |