Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 7/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SDCBP | O00560 | 1/20 | 0.47 |
| ▸ | SDC2 | P34741 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654474 | 1.00 | HPGD (0.55) | HPGDCNR2CNR1KEAP1NFE2L2 | |
| SCHEMBL4412844 | 0.87 | POLB (0.59) | HPGDCNR2CNR1PSMB8PSMB5 | |
| SCHEMBL4412847 | 0.87 | POLB (0.59) | HPGDCNR2CNR1PSMB8PSMB5 | |
| SCHEMBL10432164 | 0.87 | POLB (0.59) | HPGDCNR2CNR1PSMB8PSMB5 | |
| SCHEMBL28196545 | 0.86 | HPGD (0.54) | HPGDCNR2CNR1KEAP1NFE2L2 | |
| SCHEMBL16312234 | 0.84 | HTT (0.61) | CNR2MAPTALDH1A1 | |
| SCHEMBL7361586 | 0.84 | ALDH1A1 (0.67) | HPGDTSHRMAPTGAASDCBP | |
| SCHEMBL6136486 | 0.83 | HPGD (0.58) | HPGDCNR2CNR1KEAP1NFE2L2 | |
| SCHEMBL6136490 | 0.83 | HPGD (0.58) | HPGDCNR2CNR1KEAP1NFE2L2 | |
| SCHEMBL16312237 | 0.83 | PSMB8 (0.52) | PSMB8PSMB5MAPK1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |