Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 15/20 | 0.73 |
| ▸ | ACE2 | Q9BYF1 | 10/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654654 | 1.00 | ACE (0.73) | ACEACE2TSHR | |
| SCHEMBL10661168 | 0.99 | ACE (0.72) | ACEACE2TSHR | |
| SCHEMBL10661171 | 0.91 | ACE (0.61) | ACEACE2TSHR | |
| SCHEMBL10668559 | 0.88 | ACE (0.68) | ACEACE2TSHR | |
| SCHEMBL7272049 | 0.85 | ACE (0.74) | ACEACE2 | |
| SCHEMBL9098688 | 0.85 | ACE (0.74) | ACEACE2 | |
| SCHEMBL16375206 | 0.85 | TSHR (0.63) | ACEACE2TSHR | |
| SCHEMBL14906472 | 0.85 | ACE (0.59) | ACEACE2TSHR | |
| SCHEMBL14906468 | 0.85 | ACE (0.59) | ACEACE2TSHR | |
| SCHEMBL11122708 | 0.85 | ACE (1.00) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719200-A | Amino acid derivatives and antihypertensive drugs containing the same | AJINOMOTO CO., INC. (JP) | 1988-01-12 | — | — | US | disclosed |