Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 16/20 | 0.74 |
| ▸ | ACE2 | Q9BYF1 | 10/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098688 | 1.00 | ACE (0.74) | ACEACE2 | |
| SCHEMBL10731797 | 0.89 | ACE (0.64) | ACEACE2 | |
| SCHEMBL10733989 | 0.89 | ACE (0.64) | ACEACE2 | |
| SCHEMBL10668559 | 0.88 | ACE (0.68) | ACEACE2 | |
| SCHEMBL10655570 | 0.87 | ACE (0.76) | ACEACE2 | |
| SCHEMBL10656703 | 0.87 | ACE (0.76) | ACEACE2 | |
| SCHEMBL33721990 | 0.87 | ACE (0.64) | ACEACE2 | |
| SCHEMBL18281685 | 0.86 | ACE (0.61) | ACEACE2 | |
| SCHEMBL10736853 | 0.86 | ACE (0.61) | ACEACE2 | |
| SCHEMBL11435575 | 0.86 | ACE (0.71) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352295-B2 | BIODADHESION DRUG CARRIERS FOR ENDOTHELIAL AND EPITHELIAL UPTAKE AND LESIONAL LOCALIZATION OF THERAPEUTIC AND DIAGNOSTIC AGENTS | ACCESS PHARMA INC (US) | 1996-04-10 | — | — | EP | claimed |
| EP-0352295-B1 | BIODADHESION DRUG CARRIERS FOR ENDOTHELIAL AND EPITHELIAL UPTAKE AND LESIONAL LOCALIZATION OF THERAPEUTIC AND DIAGNOSTIC AGENTS | Access Pharmaceuticals, Inc. (US) | 1993-06-16 | — | — | EP | claimed |
| EP-0352295-A1 | BIODADHESION DRUG CARRIERS FOR ENDOTHELIAL AND EPITHELIAL UPTAKE AND LESIONAL LOCALIZATION OF THERAPEUTIC AND DIAGNOSTIC AGENTS. | RANNEY DAVID F | 1990-01-31 | — | — | EP | claimed |
| WO-1988007365-A1 | BIODADHESION DRUG CARRIERS FOR ENDOTHELIAL AND EPITHELIAL UPTAKE AND LESIONAL LOCALIZATION OF THERAPEUTIC AND DIAGNOSTIC AGENTS | RANNEY, DAVID, F. (US) | 1988-10-06 | — | — | WO | claimed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | claimed |
| WO-2002059279-A2 | PREPARATION OF REPLICATING KUPFFER CELLS AND THEIR USE IN DIAGNOSIS AND THERAPY | CALIFORNIA INSTITUTE OF MOLECULAR MEDICINE (US) | 2002-08-01 | — | — | WO | disclosed |
| EP-0352295-B2 | BIODADHESION DRUG CARRIERS FOR ENDOTHELIAL AND EPITHELIAL UPTAKE AND LESIONAL LOCALIZATION OF THERAPEUTIC AND DIAGNOSTIC AGENTS | ACCESS PHARMA INC (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0316218-B1 | L-PROLINE DERIVATIVES, THEIR PREPARATION AND BIOLOGICAL APPLICATIONS THEREOF | EKITA Investments N.V. (NA) | 1993-09-15 | — | — | EP | disclosed |
| US-5108759-A | Endothelial envelopment drug carriers | ACCESS PHARMACEUTICALS, INC. | 1992-04-28 | — | — | US | disclosed |
| US-5106731-A | Kit for cancer diagnosis | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-04-21 | — | — | US | disclosed |
| US-4925678-A | AMPHOTERICIN, MICROSPHERES | ACCESS PHARMACEUTICALS, INC. | 1990-05-15 | — | — | US | disclosed |
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| US-4695582-A | Inhibitors of angiotensin converting enzyme | UNIVERSITY OF MIAMI (US) | 1987-09-22 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
| US-4335041-A | BENZOYLPHENYLALANYLALANYLPROLINE AS SUBSTRATE | VENTREX LABORATORIES, INC. (US) | 1982-06-15 | — | — | US | disclosed |
| US-4335041-A | BENZOYLPHENYLALANYLALANYLPROLINE AS SUBSTRATE | VENTREX LABORATORIES, INC. (US) | 1982-06-15 | — | — | US | disclosed |
| US-4276378-A | HYDROLYZING HIPPURIC ACID-HISTIDINELEUCINE OLIGOPEPTIDE | VENTREX LABORATORIES, INC., A CORP. OF DE. | 1981-06-30 | — | — | US | disclosed |
| US-4260682-A | High sensitivity assays for angiotensin converting enzyme | VENTREX LABORATORIES, INC. | 1981-04-07 | — | — | US | disclosed |
| US-4260682-A | High sensitivity assays for angiotensin converting enzyme | VENTREX LABORATORIES, INC. | 1981-04-07 | — | — | US | disclosed |