Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440766 | 0.86 | NOS3 (0.57) | AOC3HSD17B10TSHRALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL11675533 | 0.85 | NOS3 (0.56) | AOC3HSD17B10TSHRALDH1A1NPSR1 | |
| SCHEMBL4362393 | 0.81 | AOC3 (0.60) | AOC3HSD17B10TSHRALDH1A1NPSR1 | |
| SCHEMBL1948819 | 0.80 | AOC3 (0.58) | AOC3HSD17B10TSHRALDH1A1NPSR1 | |
| SCHEMBL1696515 | 0.80 | AOC3 (0.62) | AOC3HSD17B10TSHRALDH1A1NPSR1 | |
| SCHEMBL8421131 | 0.79 | AOC3 (0.58) | AOC3HSD17B10TSHRALDH1A1NPSR1 | |
| SCHEMBL14752838 | 0.78 | NPSR1 (0.55) | AOC3HSD17B10TSHRALDH1A1NPSR1 | |
| SCHEMBL15103037 | 0.78 | AOC3 (0.57) | AOC3HSD17B10TSHRALDH1A1NPSR1 | |
| SCHEMBL8421120 | 0.78 | AOC3 (0.57) | AOC3HSD17B10TSHRALDH1A1NPSR1 | |
| SCHEMBL10781529 | 0.78 | AOC3 (0.57) | AOC3HSD17B10TSHRALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157267-B1 | SUBSTITUTED BENZOPYRANS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1988-11-23 | — | — | EP | disclosed |
| US-4659737-A | Substituted aminomethyl benzopyrans having anti-hypertensive activities | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| US-4647579-A | Circulation active novel substituted 4-hydroxy-benzopyrans | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-03 | — | — | US | disclosed |
| EP-0158164-A2 | Substituted 4-hydroxy-benzopyrans, process for their preparation and their use in medicines | BAYER AG (DE) | 1985-10-16 | — | — | EP | disclosed |
| EP-0157267-A2 | Substituted benzopyrans, process for their preparation and their use in medicines | BAYER AG (DE) | 1985-10-09 | — | — | EP | disclosed |