SCHEMBL10654946

SCHEMBL10654946

COc1cn[nH]c(=O)c1OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.57
ALDH1A1 P00352 3/20 0.57
HPGD P15428 2/20 0.57
HSD17B10 Q99714 2/20 0.57
MAPK1 P28482 1/20 0.57
GAA P10253 1/20 0.42
LCK P06239 2/20 0.39
TIPARP Q7Z3E1 2/20 0.38
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
GLA P06280 1/20 0.38
BRD4 O60885 2/20 0.37
AXL P30530 1/20 0.37
POLB P06746 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13906524 0.79 ALDH1A1 (0.49) KDM4EALDH1A1HPGDHSD17B10MAPK1
SCHEMBL13906526 0.78 ALDH1A1 (0.47) KDM4EALDH1A1HPGDHSD17B10MAPK1
SCHEMBL5844344 0.78 POLB (0.48) KDM4EALDH1A1HPGDHSD17B10MAPK1
SCHEMBL13914376 0.78 ALDH1A1 (0.47) KDM4EALDH1A1HPGDHSD17B10MAPK1
SCHEMBL3758540 0.73 ALDH1A1 (1.00) KDM4EALDH1A1HPGDHSD17B10MAPK1
SCHEMBL8242112 0.73 KDM4E (0.44) KDM4EALDH1A1HPGDHSD17B10MAPK1
SCHEMBL31244613 0.70 POLB (0.55) KDM4EALDH1A1HPGDHSD17B10MAPK1
SCHEMBL3977212 0.69 ALDH1A1 (0.51) KDM4EALDH1A1HPGDHSD17B10MAPK1
SCHEMBL15577465 0.69 MAPK14 (0.45) KDM4EALDH1A1HPGDHSD17B10MAPK1
SCHEMBL12778746 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0128530-B1 SUBSTITUTED 4,5-DIMETHOXYPYRIDAZONES, PROCESS FOR THEIR PREPARATION, HERBICIDES CONTAINING THEM AND THEIR USE IN COMBATING THE GROWTH OF UNDESIRABLE PLANTS BASF Aktiengesellschaft (DE) 1988-04-27 EP claimed
US-4576630-A Substituted 4,5-dimethoxypyridazones, herbicides containing these compounds, and their use for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1986-03-18 US claimed
EP-0085785-B1 SUBSTITUTED 4,5-DIMETHOXY-PYRIDAZINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR COMBATING UNDESIRABLE PLANTS BASF Aktiengesellschaft (DE) 1985-12-11 EP claimed
US-4523946-A Substituted 4,5-dimethoxypyridazones and their use for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1985-06-18 US claimed
EP-0128530-A1 Substituted 4,5-dimethoxypyridazones, process for their preparation, herbicides containing them and their use in combating the growth of undesirable plants BASF Aktiengesellschaft (DE) 1984-12-19 EP claimed
EP-0085785-A1 Substituted 4,5-dimethoxy-pyridazinones, process for their preparation and their use for combating undesirable plants BASF Aktiengesellschaft (DE) 1983-08-17 EP claimed
EP-0128530-B1 SUBSTITUTED 4,5-DIMETHOXYPYRIDAZONES, PROCESS FOR THEIR PREPARATION, HERBICIDES CONTAINING THEM AND THEIR USE IN COMBATING THE GROWTH OF UNDESIRABLE PLANTS BASF Aktiengesellschaft (DE) 1988-04-27 EP disclosed
EP-0128530-B1 SUBSTITUTED 4,5-DIMETHOXYPYRIDAZONES, PROCESS FOR THEIR PREPARATION, HERBICIDES CONTAINING THEM AND THEIR USE IN COMBATING THE GROWTH OF UNDESIRABLE PLANTS BASF Aktiengesellschaft (DE) 1988-04-27 EP disclosed
US-4576630-A Substituted 4,5-dimethoxypyridazones, herbicides containing these compounds, and their use for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1986-03-18 US disclosed
US-4576630-A Substituted 4,5-dimethoxypyridazones, herbicides containing these compounds, and their use for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1986-03-18 US disclosed
US-4576630-A Substituted 4,5-dimethoxypyridazones, herbicides containing these compounds, and their use for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1986-03-18 US disclosed
EP-0085785-B1 SUBSTITUTED 4,5-DIMETHOXY-PYRIDAZINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR COMBATING UNDESIRABLE PLANTS BASF Aktiengesellschaft (DE) 1985-12-11 EP disclosed
EP-0085785-B1 SUBSTITUTED 4,5-DIMETHOXY-PYRIDAZINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR COMBATING UNDESIRABLE PLANTS BASF Aktiengesellschaft (DE) 1985-12-11 EP disclosed
US-4523946-A Substituted 4,5-dimethoxypyridazones and their use for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1985-06-18 US disclosed
US-4523946-A Substituted 4,5-dimethoxypyridazones and their use for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1985-06-18 US disclosed
EP-0128530-A1 Substituted 4,5-dimethoxypyridazones, process for their preparation, herbicides containing them and their use in combating the growth of undesirable plants BASF Aktiengesellschaft (DE) 1984-12-19 EP disclosed
EP-0128530-A1 Substituted 4,5-dimethoxypyridazones, process for their preparation, herbicides containing them and their use in combating the growth of undesirable plants BASF Aktiengesellschaft (DE) 1984-12-19 EP disclosed
EP-0128530-A1 Substituted 4,5-dimethoxypyridazones, process for their preparation, herbicides containing them and their use in combating the growth of undesirable plants BASF Aktiengesellschaft (DE) 1984-12-19 EP disclosed
EP-0085785-A1 Substituted 4,5-dimethoxy-pyridazinones, process for their preparation and their use for combating undesirable plants BASF Aktiengesellschaft (DE) 1983-08-17 EP disclosed
EP-0085785-A1 Substituted 4,5-dimethoxy-pyridazinones, process for their preparation and their use for combating undesirable plants BASF Aktiengesellschaft (DE) 1983-08-17 EP disclosed