SCHEMBL10655463

SCHEMBL10655463

O=C1CCCCC(C2CCC(=O)N2)N1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
PKM P14618 1/20 0.42
SRD5A1 P18405 1/20 0.38
CRBN Q96SW2 2/20 0.37
FKBP5 Q13451 1/20 0.37
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
OR51E2 Q9H255 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
PARP1 P09874 1/20 0.32
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
HSD17B10 Q99714 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRL1 P41146 1/20 0.31
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7264845 0.93 SRD5A1 (0.39) ALDH1A1PKMSRD5A1CRBNFKBP5
SCHEMBL1672296 0.93 ALDH1A1 (0.44) ALDH1A1PKMSRD5A1CRBNFKBP5
SCHEMBL7263026 0.87 ALDH1A1 (0.42) ALDH1A1PKMSRD5A1CRBNFKBP5
SCHEMBL17338063 0.84 ALDH1A1 (0.36) ALDH1A1PKMSRD5A1CRBNFKBP5
SCHEMBL6652266 0.82 KMT2A (0.35) ALDH1A1PKMCRBNFKBP5CA1
SCHEMBL26673240 0.81 SRD5A1 (0.38) ALDH1A1PKMSRD5A1CRBNCA1
SCHEMBL24567493 0.80 SRD5A1 (0.35) ALDH1A1PKMSRD5A1
SCHEMBL8465326 0.79 ALDH1A1 (0.36) ALDH1A1PKMSRD5A1LMNATSHR
SCHEMBL6638258 0.79 ALDH1A1 (0.36) ALDH1A1PKMSRD5A1LMNATSHR
SCHEMBL18150856 0.79 SRD5A1 (0.37) ALDH1A1PKMSRD5A1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315616-B2 Blocked prepolymers and acrylic plastisol compositions comprising the blocked prepolymers DOW GLOBAL TECHNOLOGIES LLC (US) 2016-04-19 US disclosed
EP-2736936-B1 BLOCKED PREPOLYMERS AND ACRYLIC PLASTISOL COMPOSITIONS COMPRISING THE BLOCKED PREPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-11-04 EP disclosed
EP-2736936-A1 BLOCKED PREPOLYMERS AND ACRYLIC PLASTISOL COMPOSITIONS COMPRISING THE BLOCKED PREPOLYMERS Dow Global Technologies LLC (US) 2014-06-04 EP disclosed
WO-2013016265-A1 BLOCKED PREPOLYMERS AND ACRYLIC PLASTISOL COMPOSITIONS COMPRISING THE BLOCKED PREPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-01-31 WO disclosed
US-4786691-A PROTECTIVE AUTOMOBILE COATINGS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-22 US disclosed
EP-0107402-B1 EPOXY ESTER RESIN AND NOVEL THERMOSETTING COATING COMPOSITION COMPRISING SAME FORD MOTOR COMPANY LIMITED (GB) 1988-11-17 EP disclosed
US-4713425-A HYDROXY FUNCTIONAL EPOXY ESTER RESIN, POLYLACTONE, BLOCKED POLYISOCYANATE; FOR AUTOMOBILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-12-15 US disclosed
US-4581424-A EPOXY-POLYESTER GRAFT POLYMERS, AUTOMOBILES FORD MOTOR COMPANY (US) 1986-04-08 US disclosed
US-4579917-A EPOXY-POLYESTER GRAFT POLYMER CROSSLINKED WITH BLOCK POLYISOCYANAT FORD MOTOR COMPANY (US) 1986-04-01 US disclosed
US-4574146-A EPOXY-POLYESTER GRAFT POLYMERS FORD MOTOR COMPANY (US) 1986-03-04 US disclosed
EP-0152413-A4 THERMOSETTING COATING COMPOSITION USEFUL AS CHIP RESISTANT PRIMER. FORD MOTOR CO (GB) 1986-02-13 EP disclosed
US-4554332-A EPOXY RESIN-LACTONE GRAFT POLYMER FORD MOTOR COMPANY (US) 1985-11-19 US disclosed
EP-0152413-A1 THERMOSETTING COATING COMPOSITION USEFUL AS CHIP RESISTANT PRIMER. FORD MOTOR CO (GB) 1985-08-28 EP disclosed
US-4533534-A SPRAYABLE HIGH-SOLIDS SOLUTION OF EPOXY-POLYESTER COPOLYMER AND BLOCKED ISOCYANATE FORD MOTOR COMPANY (US) 1985-08-06 US disclosed
US-4533684-A EPOXY-POLYESTER GRAFT COPOLYMER, BLOCKED POLYISOCYANATE FORD MOTOR COMPANY (US) 1985-08-06 US disclosed
WO-1985000375-A1 THERMOSETTING COATING COMPOSITION USEFUL AS CHIP RESISTANT PRIMER FORD MOTOR COMPANY (US) 1985-01-31 WO disclosed
EP-0107402-A1 Epoxy ester resin and novel thermosetting coating composition comprising same FORD MOTOR COMPANY LIMITED (GB) 1984-05-02 EP disclosed