Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400250 | 0.88 | — | — | |
| SCHEMBL18187937 | 0.86 | MAPT (0.36) | MAPT | |
| SCHEMBL15413597 | 0.82 | — | — | |
| SCHEMBL22341313 | 0.80 | MAPT (0.30) | MAPT | |
| SCHEMBL15974515 | 0.79 | MAPT (0.39) | MAPT | |
| SCHEMBL10835748 | 0.77 | NPSR1 (0.31) | — | |
| SCHEMBL5405420 | 0.72 | — | — | |
| SCHEMBL15974184 | 0.68 | MAPT (0.34) | MAPT | |
| SCHEMBL2940601 | 0.67 | KEAP1 (0.56) | — | |
| SCHEMBL1200505 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059158-B1 | AZA PROSTACYCLINS, THEIR PREPARATION AND THERAPEUTIC APPLICATIONS | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-08-03 | — | — | EP | disclosed |
| US-4567195-A | Azaprostacyclins, their preparation and pharmaceutical use | SCHERING, AKTIENGESELLSCHAFT (DE) | 1986-01-28 | — | — | US | disclosed |
| US-4446147-A | Azaprostacyclins, their preparation and pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-05-01 | — | — | US | disclosed |
| EP-0059158-A2 | Aza prostacyclins, their preparation and therapeutic applications | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-09-01 | — | — | EP | disclosed |