SCHEMBL10656233

SCHEMBL10656233

CC(C)(C)N(C(=O)O)[C@H](/C=C/C#C[Si](C)(C)C)CC1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTSK P43235 3/20 0.34
CTSS P25774 1/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSH P09668 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10903752 0.79
SCHEMBL6245315 0.77 CTSK (0.38) CTSKCTSSCTSLCTSBCTSH
SCHEMBL1867665 0.77 CTSK (0.38) CTSKCTSSCTSLCTSBCTSH
SCHEMBL9103897 0.73 CTSK (0.33) CTSKCTSSCTSLCTSBCTSH
SCHEMBL9102349 0.70 ANPEP (0.33) CTSKCTSS
SCHEMBL5065073 0.67 CTSK (0.39) CTSKCTSSCTSLCTSBCTSH
SCHEMBL1862554 0.67 CTSK (0.39) CTSKCTSSCTSLCTSBCTSH
SCHEMBL969953 0.67 CTSK (0.36) CTSKCTSSCTSLCTSBCTSH
SCHEMBL970772 0.67 CTSK (0.36) CTSKCTSSCTSLCTSBCTSH
SCHEMBL1859132 0.66 CTSK (0.40) CTSKCTSSCTSLCTSBCTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4743585-A PEPTIDES, HYPOTENSIVE AGENTS, HYPERALDOSTERONISM WARNER-LAMBERT COMPANY (US) 1988-05-10 US disclosed