Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 7/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 6/20 | 0.58 |
| ▸ | CA12 | O43570 | 6/20 | 0.58 |
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357546 | 0.81 | CYP2D6 (0.64) | FBP1CYP2D6TSHRCA9CA12 | |
| SCHEMBL10807193 | 0.81 | FBP1 (0.64) | FBP1CYP2D6TSHRCA9CA12 | |
| SCHEMBL23699755 | 0.81 | CYP2D6 (0.68) | FBP1CYP2D6TSHRCA9CA12 | |
| SCHEMBL9678250 | 0.81 | CYP2D6 (0.59) | FBP1CYP2D6TSHRCA9CA12 | |
| SCHEMBL12646984 | 0.80 | FBP1 (0.62) | FBP1CYP2D6TSHRCA9CA12 | |
| SCHEMBL7781184 | 0.80 | CYP2D6 (0.66) | FBP1CYP2D6TSHRCA9CA12 | |
| SCHEMBL11068405 | 0.79 | FBP1 (0.61) | FBP1CYP2D6TSHRCA9CA12 | |
| SCHEMBL29463716 | 0.79 | FBP1 (0.61) | FBP1CYP2D6TSHRCA9CA12 | |
| SCHEMBL23732688 | 0.78 | CYP2D6 (0.56) | FBP1CYP2D6TSHRCA9CA12 | |
| SCHEMBL11287638 | 0.78 | CYP2D6 (0.64) | FBP1CYP2D6TSHRCA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177740-B1 | ACYLATED SACCHARINE DERIVATIVES | BAYER AG (DE) | 1988-09-28 | — | — | EP | disclosed |
| US-4713389-A | Fungicidally and bactericidally active acylated saccharin derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | disclosed |
| EP-0177740-A1 | Acylated saccharine derivatives | BAYER AG (DE) | 1986-04-16 | — | — | EP | disclosed |