Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653812 | 0.90 | NPC1 (0.50) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL9653690 | 0.85 | MAPT (0.42) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL9652682 | 0.84 | ALDH1A1 (0.44) | NPC1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9653773 | 0.84 | MAPT (0.42) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL9652724 | 0.82 | ALDH1A1 (0.42) | NPC1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9653251 | 0.82 | ALDH1A1 (0.45) | NPC1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9653285 | 0.82 | MAPT (0.46) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9653220 | 0.82 | MAPT (0.46) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9651887 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9653779 | 0.80 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4781750-A | Herbicidally active enols | ROHM AND HAAS COMPANY (US) | 1988-11-01 | — | — | US | disclosed |