Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14175495 | 0.92 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL17069795 | 0.91 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL7761501 | 0.90 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL14330279 | 0.89 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL9764152 | 0.89 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL26430366 | 0.89 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL9763730 | 0.88 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL18504299 | 0.87 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL12775025 | 0.86 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL332090 | 0.86 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743667-A | ACRYLATED SILOXXANES, OXYGEN PERMEABLE | NIPPON CONTACT LENS, INC. (JP) | 1988-05-10 | — | — | US | disclosed |