SCHEMBL9764152

SCHEMBL9764152

C=CC(=O)OCCC[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.52
ALDH1A1 P00352 4/20 0.52
CYP3A4 P08684 2/20 0.52
HPGD P15428 1/20 0.51
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
HSD17B10 Q99714 1/20 0.43
THRB P10828 2/20 0.37
ATM Q13315 1/20 0.34
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HCAR2 Q8TDS4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9763730 0.98 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL14175495 0.97 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL17069795 0.95 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL374776 0.92 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10883854 0.91 TSHR (0.54) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL18504299 0.91 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL14330279 0.90 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7519220 0.90 TSHR (0.46) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL332090 0.90 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10656377 0.89 TSHR (0.60) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4988788-A Room temperature-curable coating composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-01-29 US claimed
US-8329067-B2 Method of producing color filter and color filter DAI NIPPON PRINTING CO., LTD. (JP) 2012-12-11 US disclosed
US-20090114888-A1 METHOD OF PRODUCING COLOR FILTER AND COLOR FILTER DAI NIPPON PRINTING CO., LTD. (JP) 2009-05-07 US disclosed
US-4743667-A ACRYLATED SILOXXANES, OXYGEN PERMEABLE NIPPON CONTACT LENS, INC. (JP) 1988-05-10 US disclosed