⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221478 | 0.91 | — | — | |
| SCHEMBL22682851 | 0.91 | — | — | |
| SCHEMBL34914 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL5465232 | 0.75 | ALDH1A1 (0.41) | — | |
| SCHEMBL17554512 | 0.73 | — | — | |
| SCHEMBL18145177 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL551724 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL1047397 | 0.73 | — | — | |
| SCHEMBL6323393 | 0.70 | ALDH1A1 (0.41) | — | |
| SCHEMBL7120115 | 0.70 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563910-B2 | Heterocyclic cannabinoid receptor antagonists | HOFFMANN-LA ROCHE INC. (US) | 2009-07-21 | — | — | US | claimed |
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |
| EP-1749002-A1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | F.HOFFMANN-LA ROCHE AG (CH) | 2007-02-07 | — | — | EP | claimed |
| WO-2005108393-A1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-17 | — | — | WO | claimed |
| US-20050250769-A1 | Heterocyclic cannabinoid receptor antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-10 | — | — | US | claimed |
| US-6048667-A | FREE RADICALS OR CATION POLYMERIZABLE OR PHOTOCROSSLINKABLE MONOMERS, SUBSTRATES AND PHOTOINITIATORS, BONDING WITH SUBSTRATES | CIBA SPECIALTY CHEMICALS CORP. (US) | 2000-04-11 | — | — | US | claimed |
| EP-0638553-A1 | Carboxylic acid amides having a terminal carboxylic acid group as aggregation inhibiting drugs | Dr. Karl Thomae GmbH (DE) | 1995-02-15 | — | — | EP | claimed |
| EP-0421752-A2 | Substituted acrylamido-penicillanic acid derivatives | Beecham Group p.l.c. (GB) | 1991-04-10 | — | — | EP | claimed |
| EP-0247431-A1 | Substituted 6-hydroxymethylcarbapenem antibiotics, process for their preparation and their use | BAYER AG (DE) | 1987-12-02 | — | — | EP | claimed |
| JP-62138469-A | — | — | None | — | — | JP | disclosed |
| WO-2024146945-A1 | NOVEL CARBOXAMIDE AND SULFONAMIDE PESTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024126650-A1 | NOVEL BICYCLIC-CARBOXAMIDE COMPOUNDS USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024089216-A1 | NOVEL SULFUR-CONTAINING HETEROARYL CARBOXAMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024033374-A1 | NOVEL ARYLCARBOXAMIDE OR ARYLTHIOAMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-02-15 | — | — | WO | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |
| EP-0638553-A1 | Carboxylic acid amides having a terminal carboxylic acid group as aggregation inhibiting drugs | Dr. Karl Thomae GmbH (DE) | 1995-02-15 | — | — | EP | disclosed |
| US-4863916-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0247431-A1 | Substituted 6-hydroxymethylcarbapenem antibiotics, process for their preparation and their use | BAYER AG (DE) | 1987-12-02 | — | — | EP | disclosed |
| JP-S62138469-A | INDOLE DERIVATIVE | YOSHITOMI PHARMACEUT IND LTD | 1987-06-22 | — | — | JP | disclosed |
| US-3970654-A | Antiviral 2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-07-20 | — | — | US | disclosed |