Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092674 | 0.77 | SUCNR1 (0.38) | TSHRSUCNR1KDM4EALDH1A1 | |
| SCHEMBL1768267 | 0.67 | — | — | |
| SCHEMBL8217572 | 0.67 | — | — | |
| SCHEMBL7092791 | 0.67 | SUCNR1 (0.32) | SUCNR1 | |
| SCHEMBL23797246 | 0.67 | HRH3 (0.45) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL22616173 | 0.67 | HRH3 (0.45) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL1709272 | 0.67 | HRH3 (0.45) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL20856976 | 0.64 | POLB (0.32) | SUCNR1 | |
| SCHEMBL20856964 | 0.64 | POLB (0.32) | SUCNR1 | |
| SCHEMBL10652438 | 0.64 | KDM4E (0.31) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219331-A3 | TARTRATE-BASED COMPOUND USEFUL AS STABILIZERS FOR POLYMERS | ICI AMERICAS INC. (US) | 1988-10-05 | — | — | EP | disclosed |
| US-4690963-A | POLYALKYL-1,4-DIOXA-8-AZASPIRO(4.5)DECANE-2,3-DICARBOXYLIC ACIDS, ESTERS OR AMIDES; POLYPROPYLENE FILMS | ICI AMERICAS INC. (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0219331-A2 | Tartrate-based compound useful as stabilizers for polymers | ICI AMERICAS INC. (US) | 1987-04-22 | — | — | EP | disclosed |