SCHEMBL7092674

SCHEMBL7092674

O=C(O)C1OC2(CCCCC2)OC1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SUCNR1 Q9BXA5 1/20 0.38
MAPK1 P28482 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
CYP2C19 P33261 1/20 0.32
USP2 O75604 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
TSHR P16473 1/20 0.30
BLM P54132 1/20 0.30
CACNA2D1 P54289 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9458211 0.85 ALDH1A1 (0.37) MAPK1NPSR1ALDH1A1KDM4EPOLB
SCHEMBL20856964 0.84 POLB (0.32) SUCNR1MAPK1NPSR1POLBGAA
SCHEMBL20856976 0.84 POLB (0.32) SUCNR1MAPK1NPSR1POLBGAA
SCHEMBL25625943 0.82
SCHEMBL22247538 0.80 MAPK1 (0.33) MAPK1NPSR1
SCHEMBL25624937 0.80 MAPK1 (0.33) MAPK1NPSR1
SCHEMBL22247527 0.80 MAPK1 (0.33) MAPK1NPSR1
SCHEMBL25624926 0.80 MAPK1 (0.33) MAPK1NPSR1
SCHEMBL9457269 0.79 PPM1B (0.42) MAPK1NPSR1ALDH1A1POLBGAA
SCHEMBL10656513 0.77 GABRP (0.38) SUCNR1ALDH1A1KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0219332-B1 TARTRATE COMPOUNDS USEFUL AS LIGHT STABILIZERS FOR PLASTICS ICI AMERICAS INC. (US) 1992-04-29 EP claimed
US-4687800-A POLYALKYL PIPERIDIN-4-YL CONTAINING ACETAL ESTERS AND AMIDES ICI AMERICAS INC. (US) 1987-08-18 US claimed
EP-0219332-A2 Tartrate compounds useful as light stabilizers for plastics ICI AMERICAS INC. (US) 1987-04-22 EP claimed
US-20030189192-A1 Stabilizing mixtures for organic polymers GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2003-10-09 US disclosed
EP-0517658-B1 Stabilisation of polymeric organic materials by using synergistic mixtures comprising sterically hindered cyclic amines and derivatives of 3-pyrazolidinone or 1,2,4-triazolidine-3,5-dione CIBA GEIGY AG (CH) 1997-01-29 EP disclosed
US-5457143-A Light, heat and oxydiation resistance CIBA-GEIGY CORPORATION (US) 1995-10-10 US disclosed
EP-0517658-A1 Stabilisation of polymeric organic materials by using synergistic mixtures comprising sterically hindered cyclic amines and derivatives of 3-pyrazolidinone or 1,2,4-triazolidine-3,5-dione CIBA-GEIGY AG (CH) 1992-12-09 EP disclosed
EP-0219332-B1 TARTRATE COMPOUNDS USEFUL AS LIGHT STABILIZERS FOR PLASTICS ICI AMERICAS INC. (US) 1992-04-29 EP disclosed
US-4687800-A POLYALKYL PIPERIDIN-4-YL CONTAINING ACETAL ESTERS AND AMIDES ICI AMERICAS INC. (US) 1987-08-18 US disclosed
EP-0219332-A2 Tartrate compounds useful as light stabilizers for plastics ICI AMERICAS INC. (US) 1987-04-22 EP disclosed