Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | QPCT | Q16769 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10739872 | 0.85 | DRD4 (0.48) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL10655159 | 0.83 | KDM4E (0.48) | — | |
| SCHEMBL10731837 | 0.83 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL10736548 | 0.83 | — | — | |
| SCHEMBL10654564 | 0.82 | — | — | |
| SCHEMBL10659233 | 0.82 | — | — | |
| SCHEMBL10733601 | 0.82 | — | — | |
| SCHEMBL10658102 | 0.80 | TSHR (0.57) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10736597 | 0.79 | TSHR (0.56) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10735085 | 0.79 | TSHR (0.56) | MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293500-A1 | 3-heteroalkyl-2,4.quinzaoline-diones | AMERICAN CYANAMID COMPANY (US) | 1988-12-07 | — | — | EP | disclosed |
| US-4680293-A | 3-imidazolylalkyl-, triazolylalkyl-, pyridinylalkyl-1,2,3-benzotriazin-4(3H)-ones and derivatives thereof | AMERICAN CYANAMID COMPANY (US) | 1987-07-14 | — | — | US | disclosed |