SCHEMBL10656599

SCHEMBL10656599

CC(=O)OC(Cl)C1CCCNNC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
CPN1 P15169 1/20 0.30
CPB2 Q96IY4 1/20 0.30
GLI1 P08151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10662143 0.84
SCHEMBL10656818 0.83 CPN1 (0.33) CPN1CPB2
SCHEMBL1784327 0.77 TSHR (0.41) TSHR
SCHEMBL6050056 0.67 CPN1 (0.45) TSHRCPN1CPB2
SCHEMBL8675012 0.63 TSHR (0.46) TSHR
SCHEMBL1051503 0.61 TSHR (0.50) TSHR
SCHEMBL11170830 0.61 TSHR (0.50) TSHR
SCHEMBL873507 0.61 TSHR (0.50) TSHR
SCHEMBL8674655 0.61 TSHR (0.44) TSHR
SCHEMBL8444779 0.61 TSHR (0.44) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4727151-A CLEAVED TO DRUGS IN VIVO BY CHEMICAL OR ENZYMATIC HYDROLYSIS INTERX RESEARCH CORPORATION (US) 1988-02-23 US disclosed
US-4160099-A Labile, non-heterocyclic quaternary ammonium salt/esters as transient derivatives INTERX RESEARCH CORPORATION 1979-07-03 US disclosed