Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.41 |
| ▸ | ELOVL1 | Q9BW60 | 3/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10771375 | 0.98 | MAPK1 (0.53) | MAPK1SLC9A1ELOVL1MPOCYP1A2 | |
| SCHEMBL21227788 | 0.96 | MAPK1 (0.51) | MAPK1SLC9A1ELOVL1MPOMAPT | |
| SCHEMBL18250695 | 0.96 | MAPK1 (0.51) | MAPK1SLC9A1ELOVL1MPOMAPT | |
| SCHEMBL293389 | 0.92 | MAPK1 (0.55) | MAPK1SLC9A1ELOVL1MPOCYP1A2 | |
| SCHEMBL25067562 | 0.80 | MAPK1 (0.44) | MAPK1SLC9A1ELOVL1CYP1A2CYP2C9 | |
| SCHEMBL25871802 | 0.80 | MAPK1 (0.44) | MAPK1ELOVL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22143644 | 0.78 | MAPK1 (0.58) | MAPK1ELOVL1MPOCYP1A2CYP2C19 | |
| SCHEMBL11499176 | 0.78 | SLC9A1 (0.42) | MAPK1SLC9A1MPOCYP1A2CYP2C9 | |
| SCHEMBL438493 | 0.77 | KDM4E (0.46) | SLC9A1MPOTLR8ALDH1A1 | |
| SCHEMBL31287918 | 0.77 | SLC9A1 (0.44) | MAPK1SLC9A1MPOALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296381-A1 | Substituted 5-methyl amino-1-aryl pyrazoles | BAYER AG (DE) | 1988-12-28 | — | — | EP | disclosed |