Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.49 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.49 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23322830 | 0.84 | LMNA (0.46) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL11024545 | 0.82 | LMNA (0.61) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL11040533 | 0.81 | LMNA (0.44) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL11159032 | 0.81 | LMNA (0.44) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL25965763 | 0.79 | LMNA (0.42) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL10656213 | 0.76 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL11771756 | 0.75 | LMNA (0.50) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL12500772 | 0.75 | LMNA (0.56) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL15616807 | 0.75 | LMNA (0.46) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 | |
| SCHEMBL3823927 | 0.74 | SMN1; SMN2 (0.62) | LMNASMN1; SMN2CYP3A4CYP2D6MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0265506-A1 | A PRODRUG FORM OF 5-FLUOROURACIL AND A METHOD OF TREATMENT OF CANCER | FARMACEUTISK LABORATORIUM FERRING A/S (DK) | 1988-05-04 | — | — | EP | claimed |
| WO-1987006581-A1 | A PRODRUG FORM OF 5-FLUOROURACIL AND A METHOD OF TREATMENT OF CANCER | FARMACEUTISK LABORATORIUM FERRING A/S (DK) | 1987-11-05 | — | — | WO | claimed |
| EP-0265506-A1 | A PRODRUG FORM OF 5-FLUOROURACIL AND A METHOD OF TREATMENT OF CANCER | FARMACEUTISK LABORATORIUM FERRING A/S (DK) | 1988-05-04 | — | — | EP | disclosed |
| WO-1987006581-A1 | A PRODRUG FORM OF 5-FLUOROURACIL AND A METHOD OF TREATMENT OF CANCER | FARMACEUTISK LABORATORIUM FERRING A/S (DK) | 1987-11-05 | — | — | WO | disclosed |