Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 10/20 | 0.47 |
| ▸ | CTSA | P10619 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | GLA | P06280 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134652 | 1.00 | SCNN1A (0.47) | SCNN1ACTSAGRM5ALDH1A1HSD17B10 | |
| SCHEMBL1134506 | 1.00 | SCNN1A (0.47) | SCNN1ACTSAGRM5ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL1134554 | 0.98 | SCNN1A (0.46) | SCNN1ACTSAGRM5ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL1134643 | 0.98 | SCNN1A (0.46) | SCNN1ACTSAGRM5ALDH1A1HSD17B10 | |
| SCHEMBL1134544 | 0.88 | SCNN1A (0.45) | SCNN1ACTSAGRM5ALDH1A1HSD17B10 | |
| SCHEMBL1134548 | 0.88 | SCNN1A (0.45) | SCNN1ACTSAGRM5ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL2074344 | 0.87 | ALDH1A1 (0.44) | SCNN1ACTSAGRM5ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL1134531 | 0.87 | ALDH1A1 (0.44) | SCNN1ACTSAGRM5ALDH1A1HSD17B10 | |
| SCHEMBL1134633 | 0.86 | SCNN1A (0.43) | SCNN1ACTSAGRM5ALDH1A1HSD17B10 | |
| SCHEMBL1134504 | 0.85 | SCNN1A (0.46) | SCNN1ACTSAGRM5ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293170-A1 | Aminomethylphenolic pyrazines, their preparation and use | ICI AMERICAS INC. (US) | 1988-11-30 | — | — | EP | disclosed |