Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 17/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655020 | 0.96 | ELANE (0.56) | ELANE | |
| SCHEMBL10660801 | 0.94 | ELANE (0.61) | ELANEMEN1KMT2A | |
| SCHEMBL2076448 | 0.81 | ELANE (0.51) | ELANE | |
| SCHEMBL10657580 | 0.79 | DAPK3 (0.37) | ELANE | |
| SCHEMBL10662279 | 0.77 | ELANE (0.45) | ELANEMEN1KMT2A | |
| SCHEMBL10489719 | 0.76 | ELANE (0.64) | ELANE | |
| SCHEMBL10659156 | 0.74 | ELANE (0.69) | ELANEKMT2A | |
| SCHEMBL2077629 | 0.73 | ELANE (0.62) | ELANEKMT2A | |
| SCHEMBL10489845 | 0.73 | ELANE (0.64) | ELANE | |
| SCHEMBL10489803 | 0.72 | ELANE (0.63) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745116-A | INHIBITORS OF SERINE PROTEASE | SYNTEX (U.S.A.) INC. (US) | 1988-05-17 | — | — | US | disclosed |
| US-4665070-A | SERINE PROTEINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1987-05-12 | — | — | US | disclosed |