Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657656 | 1.00 | PDE3B (0.42) | PDE3BPDE3AP2RY12BRD4KMT2A | |
| SCHEMBL10657105 | 0.97 | FFAR1 (0.43) | PDE3BPDE3AP2RY12BRD4KMT2A | |
| SCHEMBL10657100 | 0.97 | FFAR1 (0.43) | PDE3BPDE3AP2RY12BRD4KMT2A | |
| SCHEMBL10655606 | 0.83 | MAPT (0.49) | PDE3BPDE3AP2RY12BRD4KMT2A | |
| SCHEMBL10655609 | 0.83 | MAPT (0.49) | PDE3BPDE3AP2RY12BRD4KMT2A | |
| SCHEMBL10659586 | 0.81 | PDE3B (0.51) | PDE3BPDE3AP2RY12KMT2AHPGD | |
| SCHEMBL10659590 | 0.81 | PDE3B (0.51) | PDE3BPDE3AP2RY12KMT2AHPGD | |
| SCHEMBL10659845 | 0.81 | MAPT (0.48) | PDE3BPDE3AP2RY12BRD4KMT2A | |
| SCHEMBL10659850 | 0.81 | MAPT (0.48) | PDE3BPDE3AP2RY12BRD4KMT2A | |
| SCHEMBL7315331 | 0.80 | ALDH1A1 (0.48) | PDE3BPDE3AP2RY12BRD4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775674-A | CARDIOTONIC AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-10-04 | — | — | US | disclosed |