Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657698 | 1.00 | REN (0.55) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10662212 | 0.96 | REN (0.60) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10659887 | 0.96 | REN (0.60) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10656796 | 0.88 | REN (0.57) | REN | |
| SCHEMBL10656802 | 0.88 | REN (0.57) | REN | |
| SCHEMBL10657717 | 0.88 | REN (0.72) | REN | |
| SCHEMBL10659915 | 0.86 | PSEN1 (0.59) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10664115 | 0.85 | REN (0.62) | REN | |
| SCHEMBL10664132 | 0.85 | REN (0.62) | REN | |
| SCHEMBL10659894 | 0.84 | REN (0.78) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757050-A | Urea, amide group-containing | E. R. SQUIBB SONS, INC. (US) | 1988-07-12 | — | — | US | claimed |
| US-4757050-A | Urea, amide group-containing | E. R. SQUIBB SONS, INC. (US) | 1988-07-12 | — | — | US | disclosed |