Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.53 |
| ▸ | RORC | P51449 | 2/20 | 0.53 |
| ▸ | RORB | Q92753 | 2/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78221 | 0.86 | MRGPRX4 (0.61) | JAK2JAK1TYK2CES2MRGPRX4 | |
| SCHEMBL477732 | 0.86 | JAK2 (0.55) | JAK2JAK1TYK2CES2RORC | |
| SCHEMBL27353325 | 0.86 | GLA (0.55) | JAK2JAK1TYK2CES2RORC | |
| SCHEMBL629096 | 0.85 | CASP1 (0.55) | JAK2JAK1TYK2CES2RORC | |
| Hydrochloric Acid SCHEMBL18861026 | 0.85 | MRGPRX4 (0.59) | JAK2JAK1TYK2CES2MRGPRX4 | |
| SCHEMBL30740081 | 0.85 | JAK2 (0.57) | JAK2JAK1TYK2CES2RORC | |
| SCHEMBL1199588 | 0.85 | JAK2 (0.57) | JAK2JAK1TYK2CES2RORC | |
| SCHEMBL30094862 | 0.85 | JAK2 (0.54) | JAK2JAK1TYK2CES2RORC | |
| SCHEMBL15697514 | 0.85 | JAK2 (0.54) | JAK2JAK1TYK2CES2RORC | |
| SCHEMBL1614585 | 0.84 | IL2 (0.53) | JAK2JAK1TYK2CES2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792635-A | Symmetric benzophenones substituted by groups containing fluorine | BAYER AKTIENGESELLSCHAFT (DE) | 1988-12-20 | — | — | US | disclosed |
| EP-0156278-B1 | PROCESS FOR THE PREPARATION OF SYMMETRICAL BENZOPHENONES SUBSTITUTED BY FLUOR-CONTAINING GROUPS, THEIR USE AND SYMMETRICAL BENZOPHENONES SUBSTITUTED BY FLUOR-CONTAINING GROUPS | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0156278-A2 | Process for the preparation of symmetrical benzophenones substituted by fluor-containing groups, their use and symmetrical benzophenones substituted by fluor-containing groups | BAYER AG (DE) | 1985-10-02 | — | — | EP | disclosed |