Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 4/20 | 0.42 |
| ▸ | NOS3 | P29474 | 3/20 | 0.42 |
| ▸ | NOS1 | P29475 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 4/20 | 0.42 |
| ▸ | ARG1 | P05089 | 3/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29187390 | 0.95 | GSR (0.48) | OTCPOLBGSRNOS2NOS3 | |
| SCHEMBL21568530 | 0.95 | GSR (0.48) | OTCPOLBGSRNOS2NOS3 | |
| SCHEMBL30640443 | 0.89 | GSR (0.42) | OTCPOLBGSRKMT2ACYP1A2 | |
| SCHEMBL4926994 | 0.83 | DPP7 (0.47) | OTCPOLBMEN1KMT2AGAA | |
| SCHEMBL18741145 | 0.83 | GSR (0.47) | OTCGSRDDAH1NOS2NOS3 | |
| SCHEMBL22679808 | 0.82 | ALDH1A1 (0.59) | OTCPOLBGSRDDAH1MEN1 | |
| SCHEMBL31296029 | 0.82 | ALDH1A1 (0.59) | OTCPOLBGSRDDAH1MEN1 | |
| SCHEMBL22689835 | 0.81 | GSR (0.46) | OTCGSRDDAH1NOS2NOS3 | |
| SCHEMBL22689973 | 0.81 | GSR (0.46) | OTCGSRMEN1KMT2AGAA | |
| SCHEMBL27455384 | 0.81 | GSR (0.46) | OTCGSRDDAH1NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |