Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782144 | 0.91 | RAB9A (0.50) | RAB9ANPC1HTTALDH1A1JAK2 | |
| SCHEMBL3979580 | 0.87 | CYP2C19 (0.63) | RAB9ANPC1HTTALDH1A1JAK2 | |
| SCHEMBL10661628 | 0.86 | RAB9A (0.45) | RAB9ANPC1HTTALDH1A1JAK2 | |
| SCHEMBL11691631 | 0.86 | TSHR (0.51) | RAB9ANPC1HTTALDH1A1JAK2 | |
| SCHEMBL632177 | 0.85 | MAPT (0.44) | RAB9ANPC1HTTALDH1A1JAK2 | |
| SCHEMBL29431930 | 0.85 | MAPT (0.44) | RAB9ANPC1HTTALDH1A1JAK2 | |
| SCHEMBL11636036 | 0.84 | RAB9A (0.56) | RAB9ANPC1HTTALDH1A1JAK2 | |
| SCHEMBL4165355 | 0.84 | RAB9A (0.52) | RAB9ANPC1HTTALDH1A1JAK2 | |
| SCHEMBL31538078 | 0.83 | NR1H2 (0.54) | RAB9ANPC1HTTALDH1A1JAK2 | |
| SCHEMBL11012064 | 0.83 | NR1H2 (0.54) | RAB9ANPC1HTTALDH1A1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734490-A | TEXTILE DYEING AND PRINTING | CIBA-GEIGY CORPORATION (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0051563-B1 | MONO-AZO COMPOUNDS | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |
| US-4088673-A | Process for the preparation of styryl dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4041024-A | FOR POLYAMIDES AND POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-09 | — | — | US | disclosed |
| US-3971740-A | DYES FOR POLYESTER FIBERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |