SCHEMBL10658933

SCHEMBL10658933

COCC(=O)Nc1ccc(N)c(C)c1

nearest known ligand 0.73

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.73
HPGD P15428 5/20 0.64
KDM4C Q9H3R0 1/20 0.55
KMT2A Q03164 2/20 0.54
RAB9A P51151 2/20 0.54
KDM4E B2RXH2 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
PKM P14618 1/20 0.54
MAPT P10636 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
CYP2C19 P33261 1/20 0.53
ALOX12 P18054 1/20 0.53
MAPK1 P28482 1/20 0.53
HTT P42858 1/20 0.53
POLB P06746 1/20 0.51
LMNA P02545 1/20 0.49
MTNR1A P48039 1/20 0.48
MTNR1B P49286 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11877095 0.87 HPGD (0.59) ALDH1A1HPGDKDM4CKMT2ARAB9A
SCHEMBL10658526 0.83 SMN1; SMN2 (0.57) ALDH1A1HPGDKDM4CKMT2AKDM4E
SCHEMBL10659662 0.82 POLB (0.56) ALDH1A1HPGDKMT2ARAB9AKDM4E
SCHEMBL11310900 0.81 NPC1 (0.72) ALDH1A1HPGDRAB9AKDM4EMAPT
SCHEMBL15886354 0.81 ALDH1A1 (0.68) ALDH1A1HPGDKDM4CKMT2ARAB9A
SCHEMBL14426553 0.81 HPGD (0.78) ALDH1A1HPGDKDM4CKMT2ARAB9A
SCHEMBL11574628 0.81 POLB (0.54) ALDH1A1HPGDKMT2ARAB9AKDM4E
SCHEMBL9345619 0.81 POLB (0.59) ALDH1A1HPGDKMT2ARAB9AKDM4E
SCHEMBL21262587 0.80 SMN1; SMN2 (0.52) ALDH1A1HPGDKMT2ARAB9AKDM4E
SCHEMBL29965600 0.80 SMN1; SMN2 (0.52) ALDH1A1HPGDKMT2ARAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4742160-A CATIONIC DYES; PRINTING SANDOZ LTD. (CH) 1988-05-03 US disclosed
US-4080321-A COLORFASTNESS HOECHST AKTIENGESELLSCHAFT (DT) 1978-03-21 US disclosed