Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2996553 | 0.84 | HCAR3 (0.60) | HCAR3FGFR1HPGDHSD17B10GAA | |
| SCHEMBL31159882 | 0.84 | HCAR3 (0.56) | HCAR3FGFR1HPGDHSD17B10GAA | |
| SCHEMBL31183038 | 0.83 | HCAR3 (0.55) | HCAR3FGFR1HPGDHSD17B10GAA | |
| SCHEMBL30138443 | 0.82 | HCAR3 (0.58) | HCAR3FGFR1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL3816420 | 0.82 | HCAR3 (0.54) | HCAR3FGFR1HPGDHSD17B10GAA | |
| SCHEMBL3436680 | 0.82 | HCAR3 (0.58) | HCAR3FGFR1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL1307081 | 0.81 | HCAR3 (0.50) | HCAR3FGFR1HPGDHSD17B10GAA | |
| SCHEMBL6844860 | 0.81 | HCAR3 (0.52) | HCAR3FGFR1HPGDHSD17B10GAA | |
| SCHEMBL3616090 | 0.81 | FGFR1 (0.52) | HCAR3FGFR1HPGDHSD17B10GAA | |
| SCHEMBL30930540 | 0.80 | HPGD (0.68) | HCAR3FGFR1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868205-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2011-01-11 | — | — | US | disclosed |