Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2930861 | 0.83 | — | — | |
| SCHEMBL20931262 | 0.81 | GAA (0.54) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL8153060 | 0.77 | TDP1 (0.32) | — | |
| SCHEMBL27976 | 0.74 | MGAM (0.61) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL15688315 | 0.72 | MGAM (0.58) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL8617909 | 0.70 | — | — | |
| SCHEMBL11894877 | 0.70 | TSHR (0.48) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL11756126 | 0.69 | TSHR (0.61) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL27730190 | 0.69 | TSHR (0.46) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL3441102 | 0.68 | MGAM (0.69) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766213-A | 1,4-dihydropyridines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-08-23 | — | — | US | disclosed |