SCHEMBL27976

SCHEMBL27976

COC(=O)CC(=O)CC(=O)OC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.61
GAA P10253 2/20 0.61
SI P14410 2/20 0.61
MGAM2 Q2M2H8 2/20 0.61
TSHR P16473 4/20 0.59
HSD17B10 Q99714 2/20 0.53
LMNA P02545 3/20 0.46
KDM4E B2RXH2 1/20 0.46
KMT2A Q03164 2/20 0.42
TET2 Q6N021 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 3/20 0.41
CA12 O43570 1/20 0.40
CA14 Q9ULX7 1/20 0.40
RECQL P46063 1/20 0.40
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
HSP90AB1 P08238 1/20 0.37
POLB P06746 1/20 0.37
POLA1 P09884 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15688315 0.97 MGAM (0.58) MGAMGAASIMGAM2TSHR
SCHEMBL3585736 0.88 MGAM (0.74) MGAMGAASIMGAM2TSHR
SCHEMBL115815 0.88 MGAM (0.50) MGAMGAASIMGAM2TSHR
SCHEMBL11756126 0.87 TSHR (0.61) MGAMGAASIMGAM2TSHR
SCHEMBL18914895 0.86 TSHR (0.48) MGAMGAASIMGAM2TSHR
SCHEMBL11932196 0.86 TSHR (0.48) MGAMGAASIMGAM2TSHR
SCHEMBL11779901 0.86 MGAM (0.48) MGAMGAASIMGAM2TSHR
SCHEMBL10485430 0.86 MGAM (0.48) MGAMGAASIMGAM2TSHR
SCHEMBL17522586 0.86 MGAM (0.70) MGAMGAASIMGAM2TSHR
SCHEMBL10012431 0.86 MGAM (0.48) MGAMGAASIMGAM2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1856 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116917446-B Hydroprocessing process using catalyst sequences with nickel, molybdenum and tungsten based catalysts IFP Energies Nouvelles (FR) 2026-05-26 CN claimed
US-12629669-B2 Method for rejuvenating a catalyst from a hydroprocessing and/or hydrocracking process IFP Energies Nouvelles (FR) 2026-05-19 US claimed
EP-4558588-B1 HYDROTREATMENT PROCESS USING A SEQUENCE OF CATALYSTS WITH A CATALYST BASED ON NICKEL AND TUNGSTEN ON A SILICA-ALUMINA SUPPORT IFP ENERGIES NOW (FR) 2026-05-13 EP claimed
WO-2026087561-A1 RETARDING AGENT IN ISOCYANATE COMPONENT OF POLYURETHANE/UREA CEMENTITIOUS HYBRID SYSTEMS SIKA TECHNOLOGY AG (CH) 2026-04-30 WO claimed
EP-4733284-A1 RETARDING AGENT IN ISOCYANATE COMPONENT OF POLYURETHANE/UREA CEMENTITIOUS HYBRID SYSTEMS Sika Technology AG (CH) 2026-04-29 EP claimed
US-12590254-B2 Method for hydrodesulfurisation of a petroleum fraction using a catalyst containing a graphitic material characterised by the H/C ratio thereof IFP Energies Nouvelles (FR) 2026-03-31 US claimed
US-12521702-B2 Trimetallic catalyst made from nickel, molybdenum and tungsten and use thereof in a hydrotreatment and/or hydrocracking process IFP Energies Nouvelles (FR) 2026-01-13 US claimed
EP-4251712-B1 METHOD FOR HYDRODESULFURISATION OF A PETROLEUM FRACTION USING A CATALYST CONTAINING A GRAPHITIC MATERIAL CHARACTERISED BY THE H/C RATIO THEREOF IFP ENERGIES NOW (FR) 2026-01-07 EP claimed
US-12467003-B2 Hydrotreating process using a sequence of catalyst with a catalyst based on nickel, molybdenum and tungsten IFP Energies Nouvelles (FR) 2025-11-11 US claimed
EP-4558588-A1 HYDROTREATMENT PROCESS USING A SEQUENCE OF CATALYSTS WITH A CATALYST BASED ON NICKEL AND TUNGSTEN ON A SILICA-ALUMINA SUPPORT IFP Energies nouvelles (FR) 2025-05-28 EP claimed
EP-1403264-B1 Process for the industrial synthesis of 5-amino-3-carboxymethyl-4-cyano-2-thiophenecarboxydimethylester SERVIER LAB (FR) 2004-12-29 EP claimed
CN-1500783-A Process for industrial synthesis of substituted thiophenecarboxylates and use of the compounds ɪά��ʵ���� 2004-06-02 CN claimed
US-20040059135-A1 Process for the industrial synthesis of the methyl diester of 5-amino-3-carboxymethyl-4-cyano-2-thiophenecarboxylic acid, and application to the synthesis of bivalent salts of ranelic acid and their hydrates LES LABORATOIRES SERVIER (FR) 2004-03-25 US claimed
EP-0739199-B1 ESTRADIOL PENETRATION INTENSIFIER FOR TRANSDERMAL ADMINISTRATION LOHMANN THERAPIE SYST LTS (DE) 2002-04-03 EP claimed
US-6090404-A SUSTAINED RELEASE PATCH LTS LOHMANN THERAPIE-SYSTEME GMBH (DE) 2000-07-18 US claimed
EP-0739199-A1 ESTRADIOL PENETRATION INTENSIFIER FOR TRANSDERMAL ADMINISTRATION LTS LOHMANN Therapie-Systeme GmbH (DE) 1996-10-30 EP claimed
WO-1995019162-A1 ESTRADIOL PENETRATION INTENSIFIER FOR TRANSDERMAL ADMINISTRATION LTS LOHMANN THERAPIE-SYSTEME GMBH & CO. KG (DE) 1995-07-20 WO claimed
EP-0108332-A1 Preparation of acetone dicarboxylic acid diester UBE INDUSTRIES, LTD. (JP) 1984-05-16 EP claimed
US-4333878-A MAKING 1,4-DIALKYLPYRROLE DIESTERS FROM 2-HYDROCARBOXY-1-NITROALKANE AND ENAMINE OF DIALKYL ACETONE DICARBOXYLATE ETHYL CORPORATION (US) 1982-06-08 US claimed
US-4150236-A Steroidal intermediates from the condensation product of dimethyl-3-ketoglutarate and glyoxal THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1979-04-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040059135-A1 Process for the industrial synthesis of the methyl diester of 5-amino-3-carboxymethyl-4-cyano-2-thiophenecarboxylic acid, and application to the synthesis of bivalent salts of ranelic acid and their hydrates CA7, CA2, SLC38A7 MGAM 1309/4885GAA 4098/4885SI 18/4885
US-12590254-B2 Method for hydrodesulfurisation of a petroleum fraction using a catalyst containing a graphitic material characterised by the H/C ratio thereof HMOX2, SCO2, HAO2 MGAM 1289/4885GAA 2928/4885SI 1368/4885
US-12629669-B2 Method for rejuvenating a catalyst from a hydroprocessing and/or hydrocracking process HOGA1, GK, PCK2 MGAM 1678/4885GAA 1733/4885SI 1067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.