Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 15/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657986 | 0.81 | ACE (0.53) | ACEACE2 | |
| SCHEMBL10980638 | 0.79 | ACE (0.52) | ACEACE2 | |
| SCHEMBL10656740 | 0.70 | ACE (0.56) | ACEACE2 | |
| SCHEMBL10662845 | 0.69 | ACE (0.54) | ACEACE2 | |
| SCHEMBL10657994 | 0.68 | GAA (0.38) | ACEACE2 | |
| SCHEMBL10659672 | 0.68 | ACE (0.44) | ACEACE2 | |
| SCHEMBL10659646 | 0.68 | ACE (0.44) | ACEACE2 | |
| SCHEMBL10977546 | 0.68 | ACE (0.49) | ACE | |
| SCHEMBL10758650 | 0.68 | PTPN1 (0.59) | ACE | |
| SCHEMBL10758642 | 0.68 | PTPN1 (0.59) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4736066-A | Intermediate for substituted peptide compounds | E. R. SQUIBB & SONS, INC. (US) | 1988-04-05 | — | — | US | disclosed |
| US-4535176-A | HYPOTENSIVE AGENTS, ANALGESICS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1985-08-13 | — | — | US | disclosed |
| US-4470973-A | HYPOTENSIVE AGENTS, ANALGESICS | E. R. SQUIBB & SONS, INC. (US) | 1984-09-11 | — | — | US | disclosed |