Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | TGM2 | P21980 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | FAAH | O00519 | 1/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.61 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.61 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.60 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364812 | 1.00 | HTT (0.68) | HTTTGM2LMNASMN1; SMN2FAAH | |
| SCHEMBL11973884 | 1.00 | HTT (0.68) | HTTTGM2LMNASMN1; SMN2FAAH | |
| SCHEMBL28969063 | 1.00 | HTT (0.68) | HTTTGM2LMNASMN1; SMN2FAAH | |
| SCHEMBL10599151 | 1.00 | HTT (0.68) | HTTTGM2LMNASMN1; SMN2FAAH | |
| SCHEMBL16692630 | 1.00 | HTT (0.68) | HTTTGM2LMNASMN1; SMN2FAAH | |
| Hydrochloric Acid SCHEMBL29541034 | 0.98 | HTT (0.67) | HTTTGM2LMNASMN1; SMN2FAAH | |
| Bromide SCHEMBL29171369 | 0.98 | HTT (0.67) | HTTTGM2LMNASMN1; SMN2FAAH | |
| Hydrochloric Acid SCHEMBL30025835 | 0.98 | HTT (0.67) | HTTTGM2LMNASMN1; SMN2FAAH | |
| SCHEMBL8290406 | 0.98 | HTT (0.70) | HTTTGM2LMNASMN1; SMN2FAAH | |
| SCHEMBL9325641 | 0.96 | TGM2 (0.64) | HTTTGM2LMNASMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144798-A1 | IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES | GENEVANT SCIENCES GMBH (CH) | 2023-08-03 | — | — | WO | disclosed |
| CN-116322700-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-23 | — | — | CN | disclosed |
| CN-116261458-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-13 | — | — | CN | disclosed |
| CN-115279373-A | Cyanopyrimidine inhibitors of EGFR/HER2 | 达纳-法伯癌症研究所股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| EP-3293175-B1 | METHODS FOR PURIFICATION OF SERINE PROTEASES | ALEXION PHARMA INC (US) | 2021-12-01 | — | — | EP | disclosed |
| CN-111499580-A | Substituted diaminocarboxamides and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith | 西格诺药品有限公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-111471021-A | Substituted diaminocarboxamides and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith | 西格诺药品有限公司 | 2020-07-31 | — | — | CN | disclosed |
| CN-105001165-B | Substituted diaminopyrimidines, compositions thereof, and methods of treatment therewith | 西格诺药品有限公司 | 2020-06-23 | — | — | CN | disclosed |
| CN-106946795-B | Substituted diaminocarboxamides and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith | 西格诺药品有限公司 | 2020-06-02 | — | — | CN | disclosed |
| EP-3293175-A1 | METHODS FOR PURIFICATION OF SERINE PROTEASES | Portola Pharmaceuticals, Inc. (US) | 2018-03-14 | — | — | EP | disclosed |
| EP-2938596-B1 | METHODS FOR PURIFICATION OF SERINE PROTEASES | PORTOLA PHARM INC (US) | 2017-11-01 | — | — | EP | disclosed |
| CN-1224001-A | Process for preparation of carbonates and polycarbonates | MONSANTO CO (US) | 1999-07-28 | — | — | CN | disclosed |
| US-4725680-A | AMINATION, CLEAVAGE, NEUTRALIZATION | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1988-02-16 | — | — | US | disclosed |