SCHEMBL10659991

SCHEMBL10659991

CC(C)C[C@H](N)C(=O)NCC(=O)NCC(N)=O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.42
ANPEP P15144 3/20 0.40
RNPEP Q9H4A4 2/20 0.40
DNPEP Q9ULA0 2/20 0.40
OPRD1 P41143 2/20 0.38
OPRM1 P35372 1/20 0.38
OPRK1 P41145 1/20 0.38
LARS1 Q9P2J5 1/20 0.38
PSMB5 P28074 3/20 0.37
AAK1 Q2M2I8 1/20 0.36
MMP2 P08253 2/20 0.36
TERT O14746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10664913 0.98 SLC7A5 (0.41) SLC7A5ANPEPRNPEPDNPEPOPRD1
SCHEMBL5509836 0.93 SLC7A5 (0.48) SLC7A5ANPEPRNPEPDNPEPLARS1
SCHEMBL5270305 0.93 SLC7A5 (0.48) SLC7A5ANPEPRNPEPDNPEPLARS1
Hydrochloric Acid SCHEMBL11724711 0.91 SLC7A5 (0.47) SLC7A5ANPEPRNPEPDNPEPLARS1
SCHEMBL1036014 0.86 ALDH1A1 (0.47) SLC7A5ANPEPRNPEPDNPEPOPRD1
SCHEMBL11291910 0.86 ALDH1A1 (0.47) SLC7A5ANPEPRNPEPDNPEPOPRD1
SCHEMBL2322417 0.86 ALDH1A1 (0.47) SLC7A5ANPEPRNPEPDNPEPOPRD1
SCHEMBL11291916 0.86 ALDH1A1 (0.47) SLC7A5ANPEPRNPEPDNPEPOPRD1
SCHEMBL29006326 0.86 ALDH1A1 (0.47) SLC7A5ANPEPRNPEPDNPEPOPRD1
SCHEMBL757140 0.84 CA12 (0.33) TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4719222-A LEARNING AND MEMORY ENHANCEMENT SOCIETE I.S.F. S.P.A. (IT) 1988-01-12 US disclosed
EP-0206729-A2 Pharmacologically active compounds ISF SOCIETA PER AZIONI (IT) 1986-12-30 EP disclosed