Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29375684 | 0.97 | — | — | |
| SCHEMBL10672099 | 0.97 | HRH1 (0.67) | HRH1SMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL40328 | 0.97 | — | — | |
| Water SCHEMBL4248240 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL8960759 | 0.95 | HRH1 (0.64) | HRH1SMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL30952386 | 0.95 | HRH1 (0.64) | HRH1SMN1; SMN2MAPTLIN28ATDP1 | |
| Phosphine SCHEMBL15768023 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL637197 | 0.95 | — | — | |
| SCHEMBL10695677 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL17926734 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2963017-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | Molecular Insight Pharmaceuticals, Inc. (US) | 2016-01-06 | — | — | EP | disclosed |
| EP-1482985-B1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARM INC (US) | 2015-12-23 | — | — | EP | disclosed |
| US-20110229410-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2011-09-22 | — | — | US | disclosed |
| US-7875258-B2 | For use as radiopharmaceuticals; solid phase synthesis; conjugation with DNA and G-protein-coupled receptors; high binding affinity, high labeling yield, superior retention and versatility; labeling without the need for co-ligands; simplification | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2011-01-25 | — | — | US | disclosed |
| US-20100303725-A1 | Technetium- and Rhenium-Bis(heteroaryl) Complexes, and Methods of Use Thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2010-12-02 | — | — | US | disclosed |
| US-7824661-B2 | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| EP-1713515-A4 | TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARM INC (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1718342-A4 | TECHNETIUM-AND RHENIUM-BIS(HETEROARYL) COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARM INC (US) | 2009-07-22 | — | — | EP | disclosed |
| US-20090148382-A1 | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2009-06-11 | — | — | US | disclosed |
| US-20090023787-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2009-01-22 | — | — | US | disclosed |
| EP-1718342-A1 | TECHNETIUM-AND RHENIUM-BIS(HETEROARYL) COMPLEXES, AND METHODS OF USE THEREOF | Molecular Insight Pharmaceuticals, Inc. (US) | 2006-11-08 | — | — | EP | disclosed |
| EP-1713515-A1 | TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES, AND METHODS OF USE THEREOF | Molecular Insight Pharmaceuticals, Inc. (US) | 2006-10-25 | — | — | EP | disclosed |
| EP-1482985-A4 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARM INC (US) | 2006-06-28 | — | — | EP | disclosed |
| US-20060093552-A1 | Technetium-and rhenium-bis(heteroaryl) complexes, and methods of use thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2006-05-04 | — | — | US | disclosed |
| US-20060034758-A1 | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2006-02-16 | — | — | US | disclosed |
| WO-2005079865-A1 | TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2005-09-01 | — | — | WO | disclosed |
| WO-2005079866-A1 | TECHNETIUM-AND RHENIUM-BIS(HETEROARYL) COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2005-09-01 | — | — | WO | disclosed |
| EP-1482985-A2 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | Biostream, Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| US-20030235843-A1 | Technetium-depyridine complexes, and methods of use thereof | CITIZENS BANK, N.A. | 2003-12-25 | — | — | US | disclosed |
| WO-2003077727-A2 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | BIOSTREAM, INC. (US) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060093552-A1 | Technetium-and rhenium-bis(heteroaryl) complexes, and methods of use thereof | SLC7A5, QPCT, RAB35 | HRH1 214/4885SMN1; SMN2 4625/4885MAPT 2543/4885 |
| US-20110229410-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | SLC7A5, SLC7A1, AADAT | HRH1 647/4885SMN1; SMN2 4102/4885MAPT 2979/4885 |
| US-20030235843-A1 | Technetium-depyridine complexes, and methods of use thereof | SLC7A5, DNPEP, SLC7A1 | HRH1 1283/4885SMN1; SMN2 4210/4885MAPT 2801/4885 |
| US-20100303725-A1 | Technetium- and Rhenium-Bis(heteroaryl) Complexes, and Methods of Use Thereof | SLC7A5, RAB35, AADAT | HRH1 333/4885SMN1; SMN2 4259/4885MAPT 3876/4885 |
| US-20060034758-A1 | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof | SLC7A5, RAB35, AADAT | HRH1 333/4885SMN1; SMN2 4259/4885MAPT 3876/4885 |
| US-20090148382-A1 | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof | QPCT, SLC7A5, RAB35 | HRH1 112/4885SMN1; SMN2 4750/4885MAPT 2926/4885 |
| US-20090023787-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | SLC7A5, SLC7A1, AADAT | HRH1 647/4885SMN1; SMN2 4102/4885MAPT 2979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.