Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.44 |
| ▸ | RELA | Q04206 | 7/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665432 | 1.00 | NAAA (0.49) | NAAAGAANFKB1NFKB2RELA | |
| SCHEMBL17049788 | 1.00 | NAAA (0.49) | NAAAGAANFKB1NFKB2RELA | |
| SCHEMBL10832796 | 1.00 | NAAA (0.49) | NAAAGAANFKB1NFKB2RELA | |
| SCHEMBL10472944 | 1.00 | NAAA (0.49) | NAAAGAANFKB1NFKB2RELA | |
| SCHEMBL10683017 | 1.00 | NAAA (0.49) | NAAAGAANFKB1NFKB2RELA | |
| SCHEMBL24187616 | 0.90 | GAA (0.47) | NAAAGAANFKB1NFKB2RELA | |
| SCHEMBL24187610 | 0.90 | GAA (0.47) | NAAAGAANFKB1NFKB2RELA | |
| SCHEMBL24187613 | 0.90 | GAA (0.47) | NAAAGAANFKB1NFKB2RELA | |
| SCHEMBL24187612 | 0.90 | GAA (0.47) | NAAAGAANFKB1NFKB2RELA | |
| SCHEMBL15621646 | 0.80 | IDO1 (0.47) | GAANFKB1NFKB2RELAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775670-A | BACTERICIDES, ANTIBIOTICS | E. R. SQUIBB & SONS, INC. (US) | 1988-10-04 | — | — | US | disclosed |
| EP-0048953-B1 | BETA-LACTAM ANTIBIOTICS | E.R. Squibb & Sons, Inc. (US) | 1988-03-09 | — | — | EP | disclosed |
| EP-0187355-A1 | Process for preparing beta-lactam antibiotics | E.R. Squibb & Sons, Inc. (US) | 1986-07-16 | — | — | EP | disclosed |
| US-4529698-A | Culturing Chromobacterium | E. R. SQUIBB & SONS, INC. (US) | 1985-07-16 | — | — | US | disclosed |
| EP-0048953-A2 | Beta-lactam antibiotics | E.R. Squibb & Sons, Inc. (US) | 1982-04-07 | — | — | EP | disclosed |