Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 7/20 | 0.67 |
| ▸ | CACNA1D | Q01668 | 7/20 | 0.67 |
| ▸ | CACNA1S | Q13698 | 7/20 | 0.67 |
| ▸ | CACNA1C | Q13936 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | THPO | P40225 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666271 | 0.97 | MEN1 (0.68) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL10662373 | 0.97 | MEN1 (0.69) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL7487761 | 0.91 | MEN1 (0.67) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL7480490 | 0.90 | MEN1 (0.65) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL10670264 | 0.89 | KMT2A (0.76) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL10666762 | 0.89 | CACNA1C (0.55) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL10668098 | 0.88 | CACNA1F (0.51) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL7481094 | 0.86 | CACNA1C (0.68) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL7483825 | 0.86 | CACNA1F (0.76) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| Hydrochloric Acid SCHEMBL7755544 | 0.85 | CACNA1F (0.74) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4727066-A | CARDIOVASCULAR DISORDERS | CERMOL S.A. (CH) | 1988-02-23 | — | — | US | claimed |
| US-4727066-A | CARDIOVASCULAR DISORDERS | CERMOL S.A. (CH) | 1988-02-23 | — | — | US | disclosed |
| US-4656181-A | CARDIOTONIC AGENTS | CERMOL S.A. (CH) | 1987-04-07 | — | — | US | disclosed |