Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9582472 | 0.86 | KDM4E (0.54) | KMT2AMEN1ALDH1A1GAACYP3A4 | |
| SCHEMBL5700395 | 0.73 | GAA (0.48) | KMT2AMEN1ALDH1A1GAAGFER | |
| SCHEMBL5700502 | 0.73 | KDM4E (0.50) | KMT2AMEN1ALDH1A1GAAGFER | |
| SCHEMBL5700365 | 0.73 | GAA (0.48) | KMT2AMEN1ALDH1A1GAAGFER | |
| SCHEMBL7459868 | 0.71 | KDM4E (0.69) | KMT2AALDH1A1GAAGFERLMNA | |
| SCHEMBL11890232 | 0.70 | UHRF1 (0.45) | KMT2AMEN1ALDH1A1GAAHTT | |
| SCHEMBL10673919 | 0.69 | COMT (0.50) | KMT2AMEN1ALDH1A1GAALMNA | |
| SCHEMBL10673916 | 0.69 | COMT (0.50) | KMT2AMEN1ALDH1A1GAALMNA | |
| SCHEMBL1599813 | 0.67 | KDM4E (0.42) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL18115561 | 0.66 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766136-A | Phenylsulphonyl-pyridine aldoximes as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-23 | — | — | US | disclosed |
| US-4742070-A | Arylsulphonyl-pyridinealdoxime derivatives, useful as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-03 | — | — | US | disclosed |
| EP-0236897-A1 | Arylsulfonyl-pyridinealdoxime derivatives | BAYER AG (DE) | 1987-09-16 | — | — | EP | disclosed |
| EP-0236919-A2 | Phenylsulphonyl-pyridine aldoximes | BAYER AG (DE) | 1987-09-16 | — | — | EP | disclosed |