Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.61 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.61 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.50 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674385 | 0.87 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL27851428 | 0.83 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL4414437 | 0.83 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL12404424 | 0.83 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL7504604 | 0.81 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL10689480 | 0.81 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL6582909 | 0.81 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL9363352 | 0.81 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL1004347 | 0.81 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL9843295 | 0.81 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2PDE10AGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631287-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORP. (US) | 1986-12-23 | — | — | US | claimed |
| EP-0200101-A2 | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive aliments | USV PHARMACEUTICAL CORPORATION (US) | 1986-11-05 | — | — | EP | claimed |
| US-4728668-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORPORATION (US) | 1988-03-01 | — | — | US | disclosed |
| US-4631287-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORP. (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0200101-A2 | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive aliments | USV PHARMACEUTICAL CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |