Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | MMP12 | P39900 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ATP4A | P20648 | 15/20 | 0.54 |
| ▸ | ATP4B | P51164 | 15/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068409 | 0.82 | MAPT (1.00) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21799330 | 0.81 | MAPT (0.97) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL826898 | 0.79 | MAPT (0.56) | MAPTALDH1A1POLBNPC1RAB9A | |
| SCHEMBL7314031 | 0.78 | MAPT (1.00) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL6201294 | 0.78 | MAPT (0.66) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL10663004 | 0.78 | MAPT (0.66) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL8525270 | 0.75 | SMN1; SMN2 (0.70) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL18122053 | 0.75 | MAPT (0.85) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL12297334 | 0.75 | MAPT (0.61) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8524166 | 0.74 | MAPT (0.70) | MAPTALDH1A1POLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4721721-A | 6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses | RORER PHARMACEUTICAL CORPORATION (US) | 1988-01-26 | — | — | US | claimed |
| US-4721721-A | 6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses | RORER PHARMACEUTICAL CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |