Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10663187 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL2166800 | 0.83 | KMT2A (0.49) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL2743367 | 0.83 | KMT2A (0.49) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL2166803 | 0.83 | KMT2A (0.49) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL13882780 | 0.83 | PTGES2 (0.42) | ALDH1A1MAPTKMT2AHTTTRPV1 | |
| SCHEMBL10664352 | 0.82 | PTGES2 (0.43) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL28403578 | 0.81 | KMT2A (0.47) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL2849892 | 0.80 | PIM1 (0.49) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2849894 | 0.80 | PIM1 (0.49) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13322138 | 0.80 | PIM1 (0.49) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4754067-A | REACTING A SYMETRICAL DIAMINOGUANIDINE WITH HYDROXYLAMINE HYDROCHLORIDE | AMERICAN CYANAMID COMPANY (US) | 1988-06-28 | — | — | US | disclosed |
| US-4649148-A | Insecticidal uses of diaminoguanidine hydrazone compounds | AMERICAN CYANAMID COMPANY (US) | 1987-03-10 | — | — | US | disclosed |
| US-4575560-A | ANTIFEEDING AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-03-11 | — | — | US | disclosed |