Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.62 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10663650 | 0.85 | PSMB5 (0.52) | PSMB8PSMB5TP53MEN1KMT2A | |
| SCHEMBL7948483 | 0.83 | PSMB8 (0.56) | PSMB8PSMB5MEN1KMT2AHPGD | |
| SCHEMBL10669534 | 0.82 | PSMB5 (0.49) | PSMB8PSMB5HPGDALDH1A1MAPK1 | |
| SCHEMBL10664756 | 0.82 | NPC1 (0.56) | PSMB8PSMB5TP53MEN1KMT2A | |
| SCHEMBL7956758 | 0.82 | PSMB5 (0.55) | PSMB8PSMB5TP53MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10671160 | 0.82 | PSMB8 (0.55) | PSMB8PSMB5MEN1KMT2AHPGD | |
| SCHEMBL4138516 | 0.80 | PSMB5 (0.53) | PSMB8PSMB5MEN1KMT2AHPGD | |
| SCHEMBL28465013 | 0.80 | NPC1 (0.81) | TP53MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3142808 | 0.79 | PSMB5 (0.52) | PSMB8PSMB5MEN1KMT2AHPGD | |
| SCHEMBL10671152 | 0.79 | PSMB5 (0.52) | PSMB8PSMB5TP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4751306-A | Imide intermediates for the preparation of analgesic and/or antagonist octahydrobenzofuroisoquinolines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-14 | — | — | US | disclosed |