Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | CDC25B | P30305 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27944435 | 0.87 | HCAR3 (0.56) | HCAR3LMNAALDH1A1SMN1; SMN2ATM | |
| SCHEMBL27011564 | 0.86 | HCAR3 (0.68) | HCAR3LMNAALDH1A1SMN1; SMN2ATM | |
| SCHEMBL321911 | 0.85 | HCAR3 (1.00) | HCAR3CDC25BKMT2A | |
| SCHEMBL973813 | 0.85 | HCAR3 (0.77) | HCAR3ALDH1A1CDC25BMAPTHTT | |
| Hydrochloric Acid SCHEMBL27006235 | 0.84 | PRSS1 (0.68) | HCAR3LMNAALDH1A1SMN1; SMN2ATM | |
| SCHEMBL2253159 | 0.84 | HCAR3 (0.74) | HCAR3ALDH1A1SMN1; SMN2CDC25BMAPT | |
| Hydrochloric Acid SCHEMBL321637 | 0.84 | HCAR3 (0.97) | HCAR3CDC25BKMT2A | |
| SCHEMBL506550 | 0.84 | HCAR3 (0.74) | HCAR3LMNAALDH1A1CDC25BMAPT | |
| SCHEMBL5674224 | 0.83 | HCAR3 (0.76) | HCAR3LMNAALDH1A1SMN1; SMN2ATM | |
| Hydrochloric Acid SCHEMBL18813442 | 0.83 | HCAR3 (0.72) | HCAR3LMNAALDH1A1CDC25BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103402987-A | 6-Amino-2-phenylamino-1H-benzimidazole-5-carboxamide derivatives and their use as microsomal prostaglandin E2 synthase-1 inhibitors | BOEHRINGER INGELHEIM INT | 2013-11-20 | — | — | CN | disclosed |
| US-7381423-B2 | Use of nanodispersions in cosmetic end formulations | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-06-03 | — | — | US | disclosed |
| US-4767769-A | HISTAMINE-H2 ANTAGONISTS | THE BOOTS COMPANY PLC (GB) | 1988-08-30 | — | — | US | disclosed |
| EP-0172631-A1 | Therapeutic agents | The Boots Company PLC (GB) | 1986-02-26 | — | — | EP | disclosed |