⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18715970 | 0.76 | — | — | |
| SCHEMBL19273752 | 0.76 | — | — | |
| SCHEMBL28081642 | 0.76 | — | — | |
| SCHEMBL99231 | 0.75 | — | — | |
| SCHEMBL28195973 | 0.75 | ALDH1A1 (0.47) | — | |
| SCHEMBL14721731 | 0.75 | — | — | |
| SCHEMBL7538221 | 0.72 | — | — | |
| Potassium Ion SCHEMBL7702367 | 0.72 | — | — | |
| SCHEMBL8486814 | 0.72 | ALDH1A1 (0.44) | — | |
| SCHEMBL7702355 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349130-B | A kind of synthetic method of new Florfenicol | 潍坊大有生物化工有限公司 | 2018-01-23 | — | — | CN | claimed |
| CN-106349130-A | Novel synthesis method of florfenicol | 潍坊大有生物化工有限公司 | 2017-01-25 | — | — | CN | claimed |
| CN-102548954-A | Method for producing 2,2-difluoroethylamine by hydrogenating 1,1-difluoro-2-nitroethane | BAYER CROPSCIENCE AG | 2012-07-04 | — | — | CN | claimed |
| US-4767864-A | Process for the preparation of nitromethylene derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | claimed |
| CN-116063210-B | Method for chiral synthesis of D-p-methylsulfonyl phenylserine ethyl ester | 山东国邦药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116063210-A | Method for chiral synthesis of D-p-methylsulfonyl phenylserine ethyl ester | 山东国邦药业有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-109999856-A | It is a kind of for synthesizing the catalyst, preparation method and application of 2,2- difluoroethylamine | 陕西神光化学工业有限公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-109400483-A | The production technology of one kind 2,2- difluoroethylamine | 南通宝凯化工有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-106349130-A | Novel synthesis method of florfenicol | 潍坊大有生物化工有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-102548954-B | Method for producing 2,2-difluoroethylamine by hydrogenating 1,1-difluoro-2-nitroethane | BAYER CROPSCIENCE AG | 2014-04-16 | — | — | CN | disclosed |
| CN-102548954-A | Method for producing 2,2-difluoroethylamine by hydrogenating 1,1-difluoro-2-nitroethane | BAYER CROPSCIENCE AG | 2012-07-04 | — | — | CN | disclosed |
| US-4767864-A | Process for the preparation of nitromethylene derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |
| US-4767864-A | Process for the preparation of nitromethylene derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |