Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 16/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666277 | 1.00 | HSD11B1 (0.33) | HSD11B1CYP1A2HIF1ANPC1RAB9A | |
| SCHEMBL6107480 | 0.75 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL6107091 | 0.75 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL6107095 | 0.75 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL6107096 | 0.75 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL6107867 | 0.75 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL6107872 | 0.75 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL6107873 | 0.75 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL6105758 | 0.73 | HSD11B1 (0.40) | HSD11B1 | |
| SCHEMBL6105757 | 0.73 | HSD11B1 (0.40) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762843-A | Hetero [f] fused carbocyclic pyridines as dopaminergic agents | WARNER-LAMBERT COMPANY (US) | 1988-08-09 | — | — | US | disclosed |