SCHEMBL10667145

SCHEMBL10667145

CCCCCCCCCCCCCCCCCC(=O)Nc1c(NC(=O)CCCCCCCCCCCCCCCCC)c(NC(=O)CCCCCCCCCCCCCCCCC)c(NC(=O)CCCCCCCCCCCCCCCCC)c(NC(=O)CCCCCCCCCCCCCCCCC)c1NC(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.61
FAAH O00519 4/20 0.59
MEN1 O00255 1/20 0.55
MAPK1 P28482 1/20 0.55
KMT2A Q03164 1/20 0.55
CETP P11597 1/20 0.53
CES2 O00748 3/20 0.52
CES1 P23141 3/20 0.52
SOAT1 P35610 3/20 0.51
DEGS1 O15121 1/20 0.51
LMNA P02545 1/20 0.51
POLB P06746 1/20 0.51
SOAT2 O75908 1/20 0.51
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50
GPR84 Q9NQS5 1/20 0.50
ENPP2 Q13822 1/20 0.50
DGAT2 Q96PD7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10665672 1.00 HSP90AA1 (0.61) HSP90AA1FAAHMEN1MAPK1KMT2A
SCHEMBL7777602 0.83 HSP90AA1 (0.48) HSP90AA1FAAHMEN1MAPK1KMT2A
SCHEMBL7777607 0.83 HSP90AA1 (0.48) HSP90AA1FAAHMEN1MAPK1KMT2A
SCHEMBL9446381 0.82 HPGD (0.48) HSP90AA1FAAHMEN1MAPK1KMT2A
SCHEMBL9446287 0.82 HPGD (0.48) HSP90AA1FAAHMEN1MAPK1KMT2A
SCHEMBL14106875 0.82 EP300 (0.58) MEN1KMT2ACETPSOAT1DEGS1
SCHEMBL9446346 0.82 HPGD (0.48) HSP90AA1FAAHMEN1MAPK1KMT2A
SCHEMBL9446323 0.82 HPGD (0.48) HSP90AA1FAAHMEN1MAPK1KMT2A
SCHEMBL9446288 0.82 HPGD (0.48) HSP90AA1FAAHMEN1MAPK1KMT2A
SCHEMBL9446349 0.82 HPGD (0.48) HSP90AA1FAAHMEN1MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0267210-A1 ANISOTROPIC POLYMER MATERIALS MERCK PATENT GmbH (DE) 1988-05-18 EP disclosed
WO-1987006593-A1 ANISOTROPIC POLYMER MATERIALS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1987-11-05 WO disclosed