⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2432407 | 0.74 | — | — | |
| SCHEMBL2227082 | 0.72 | — | — | |
| SCHEMBL8323712 | 0.70 | — | — | |
| SCHEMBL400697 | 0.70 | — | — | |
| SCHEMBL472918 | 0.70 | — | — | |
| SCHEMBL2406910 | 0.70 | — | — | |
| SCHEMBL6454776 | 0.70 | — | — | |
| SCHEMBL3291481 | 0.68 | — | — | |
| SCHEMBL3664471 | 0.65 | — | — | |
| SCHEMBL1199564 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0143630-A2 | Chemical compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-06-05 | — | — | EP | claimed |
| CN-114222741-A | As P2X3Suppression ofPyridopyrimidine derivatives as agents | 奇斯药制品公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-103012492-A | Blue-ray metal complex and organic electroluminescent device thereof | CHANGCHUN APPLIED CHEMISTRY | 2013-04-03 | — | — | CN | disclosed |
| CN-102333761-A | Scriptaid isosteres and their use in therapy | KARUS THERAPEUTICS LTD | 2012-01-25 | — | — | CN | disclosed |
| US-4738969-A | Substituted aminopyridones and aminoquinolones having histamine H2 -receptor blocking activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-04-19 | — | — | US | disclosed |
| US-4608380-A | HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-08-26 | — | — | US | disclosed |
| US-4600720-A | HISTAMINE H2-ANTOAGONISTS, ANTISECRETORY; THIAZOLINE, QUINAZOLINE, QUINOLINE, PYRIMIDINE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LTD. (GB) | 1986-07-15 | — | — | US | disclosed |
| US-4578459-A | HISTAMINE H2-ANTAGONISTS | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-03-25 | — | — | US | disclosed |
| US-4537779-A | HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-08-27 | — | — | US | disclosed |
| EP-0143630-A2 | Chemical compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-06-05 | — | — | EP | disclosed |
| US-4467087-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-08-21 | — | — | US | disclosed |
| US-4399142-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-08-16 | — | — | US | disclosed |
| US-4374251-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-02-15 | — | — | US | disclosed |
| US-4341787-A | ANTIHISTAMINES; ANTISECRETORY AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1982-07-27 | — | — | US | disclosed |
| US-4282221-A | Pharmacologically active compounds to inhibit H-2 histamine receptors | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-08-04 | — | — | US | disclosed |
| US-4260744-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-04-07 | — | — | US | disclosed |
| US-4181730-A | ANTISECRETORY AGENTS, IMIDAZOLYALKYLIMIDAZOLINONES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-01-01 | — | — | US | disclosed |
| US-4153793-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-05-08 | — | — | US | disclosed |
| US-4104381-A | HISTAMINE INHIBITORS, ((IMIDAZOLYLALKYL)AMINO)THIADIAZINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1978-08-01 | — | — | US | disclosed |
| US-4005205-A | PYRIMIDINE COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-01-25 | — | — | US | disclosed |