⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3291481 | 0.98 | — | — | |
| SCHEMBL2432407 | 0.74 | — | — | |
| SCHEMBL400697 | 0.70 | — | — | |
| SCHEMBL10667404 | 0.70 | — | — | |
| SCHEMBL6454776 | 0.70 | — | — | |
| SCHEMBL8323712 | 0.70 | — | — | |
| SCHEMBL2406910 | 0.70 | — | — | |
| SCHEMBL10768267 | 0.66 | GABRA5 (0.31) | — | |
| SCHEMBL3664471 | 0.65 | — | — | |
| SCHEMBL5981780 | 0.65 | BAZ2B (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114832119-B | Radioactive gel microsphere and preparation method and application thereof | 苏州大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-114832119-A | Radioactive gel microsphere and preparation method and application thereof | 苏州大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-114716366-A | 3-hydroxypyridine-4-ketone derivatives and application thereof in inhibition of renal cell iron death | 浙江大学 | 2022-07-08 | — | — | CN | disclosed |
| US-10548860-B2 | HIF-1 modulator paint formulation and uses thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-02-04 | — | — | US | disclosed |
| US-20190192452-A1 | HIF-1 MODULATOR PAINT FORMULATION AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2019-06-27 | — | — | US | disclosed |
| US-10220009-B2 | HIF-1 modulator paint formulation and uses thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-03-05 | — | — | US | disclosed |
| US-9763899-B2 | Iron chelators and use thereof for reducing transplant failure during rejection episodes | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-09-19 | — | — | US | disclosed |
| US-20170252310-A9 | Iron Chelators and Use Thereof for Reducing Transplant Failure During Rejection Episodes | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-09-07 | — | — | US | disclosed |
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |
| US-20160184244-A1 | Iron Chelators and Use Thereof for Reducing Transplant Failure During Rejection Episodes | UNIV LELAND STANFORD JUNIOR (US) | 2016-06-30 | — | — | US | disclosed |
| US-4834983-A | IRON COMPLEX OF A 3-HYDROXY-4-PYRONE, ANEMIA | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1989-05-30 | — | — | US | disclosed |
| EP-0107458-B1 | PHARMACEUTICAL COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-07-29 | — | — | EP | disclosed |
| US-4650793-A | NITROGEN-SUBSTITUTED | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-03-17 | — | — | US | disclosed |
| EP-0094149-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING A COMPLEX OF IRON WITH N-SUBSTITUTED 3-HYDROXYPYRID-2-ONE OR -4-ONE DERIVATIVES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-09-10 | — | — | EP | disclosed |
| US-4575502-A | IRON DEFICIENCY ANEMIA | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-03-11 | — | — | US | disclosed |
| EP-0159917-A2 | Pharmaceutical composition containing a hydroxypyrone-iron complex | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-10-30 | — | — | EP | disclosed |
| US-4550101-A | Iron complexes of hydroxy pyridones useful for treating iron deficiency anemia | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-10-29 | — | — | US | disclosed |
| EP-0120670-A1 | Iron III complexes of hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |
| EP-0107458-A1 | Pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-05-02 | — | — | EP | disclosed |
| EP-0094149-A2 | Pharmaceutical compositions containing a complex of iron with N-substituted 3-hydroxypyrid-2-one or -4-one derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-11-16 | — | — | EP | disclosed |